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KMID : 0604020160310010044
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Korean Journal of Critical Care Medicine
2016 Volume.31 No. 1 p.44 ~ p.48
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Successful Treatment with Empirical Erlotinib in a Patient with Respiratory Failure Caused by Extensive Lung Adenocarcinoma
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Jeong Suk-Hyeon
Um Sang-Won
Lee Hyun-Woo
Jeon Kyeong-Man
Lee Kyung-Jong
Suh Gee-Young
Chung Man-Pyo
Kim Ho-Joong
Kwon O-Jung
Choi Yoon-La
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Abstract
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We herein describe a 70-year-old woman who presented with respiratory failure due to extensive lung adenocarcinoma. Despite advanced disease, care in the intensive care unit with ventilator support was performed because she was a newly diagnosed patient and was considered to have the potential to recover after cancer treatment. Because prompt control of the cancer was needed to treat the respiratory failure, empirical treatment with an oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor was initiated before confirmation of EGFR-mutant adenocarcinoma, and the patient was successfully treated. Later, EGFR-mutant adenocarcinoma was confirmed.
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KEYWORD
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erlotinib, mechanical ventilation, non-small-cell lung cancer, respiratory failure
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